AB0491 THE IMPORTANCE OF MUSCULOSKELETAL SYMPTOM QUESTIONING IN INFLAMMATORY BOWEL DISEASES

Background: Spondyloarthritis (SpA) occurs in up to 13% of patients with inflammatory bowel disease (IBD) (1). Early diagnosis and treatment SpA IBD prevents irreversible musculoskeletal diseases. Objectives: The aim this study is emphasize the importance questioning symptoms IBD. Methods: In Hacettepe University Gastroenterology Clinic, were questioned for between March 2019 September 2020. For purpose, a validated DETAIL questionnaire (2) consisting six questions was asked (1. Have you ever had finger or toe and/or another joint swollen painful no apparent reason? 2. Occasionally, has an entire becomes swollen, making it look like ‘sausage’? 3. pain your heels? 4. back lasting at least 3 months that not injury related? 5. Do have low morning after resting improves exercise? 6. wake night because pain?). Patients 1 positive out 6 consulted rheumatology clinic, evaluated by physical examination, laboratory, imaging. Demographic clinical characteristics without compared. Results: 217 included study. Twenty previously known rheumatologic diseases excluded from 49 (24%) remaining 197 answer one question query. 39 (20%) these 16 (8.1%) them diagnosed (spondylitis: 9, peripheral arthritis: 7) (Figure 1). There significant differences terms age, gender, type, duration IBD, current treatment, fibromyalgia syndrome (FMS) depression according Beck inventory (Table Table 1. Clinical, demographic SpA. n= 23 p Age, years, median (IQR ) 47.03 (27.4) 35.9 (14.1) 0.052 Female, n (% 8 (50) 17 (74) 0.12 duration, months, 66.7 (70.7) 44.8 (70) 0.26 CD (37) 11 (48) 0.19 UC 9 (56) 12 (52) IC (7) Smoking (ever), 10 (62.5) 0.37 HLA-B27 positivity, 2 (12.5) (4.3) 0.57 Current medication, - Steroid (oral topical) (37.5) 5 (21.7) 0.31 5-ASA (68.8) 14 (61) 0.61 Immunosuppressants (AZA, MTX) (34.8) 0.86 bDMARD 4 (17.4) FMS, (6.7) (13) Inventory, level depression, -minimal (9) (22) 0.13 -mild (73) 7 (30) -moderate (18) (39) -severe 0 Harvey-Bradshaw Index activity Mayo score used. SD: standard deviation, IQR: inter-quartile range IBD: disease; SpA: , bDMARD: biological modifying anti-rheumatic drug CD: Crohn’s disease, UC: Ulcerative colitis, IC: indeterminate colitis; HBI: ASA: 5-aminosalicylic acid; AZA: azathioprine; MTX: methotrexate; FMS: Fibromyalgia Conclusion: By system patients, 20% department, nearly half (8%) findings point symptom routine outpatient clinic control patients. References: [1]Karreman MC et al. prevalence incidence axial spondyloarthritis disease: systematic review meta-analysis. Journal Colitis, 2017, 11.5: 631-642. [2]Di Carlo M DETection Arthritis Inflammatory boweL (DETAIL) questionnaire: development preliminary testing new tool screen presence spondyloarthritis. Clinical rheumatology, 2018, 37.4: 1037-1044. Figure Flow chart Disclosure Interests: None declared.